Custom Gas Mixtures

MESA Specialty Gas & Equipment is a team of professional calibration gas suppliers that offers specialty gas mixtures for a broad range of applications. Our products are used by laboratories, research and development (R&D) teams, universities, and industrial analysis applications. We have the ability to produce custom gas mixtures as well. Continue reading for additional information about our processes and standards.

Custom calibration gas mixtures and standards are manufactured using state of the art gravimetric and volumetric tools, scales, and highly sensitive instrumentation. Visit our typical mixture component page to see the most common materials available for custom specialty gas mixtures. Several cylinder sizes are also available to meet your specific content requirements. See our cylinder specifications page to look at the most common available cylinders.

Precise manufacturing of custom calibration gas mixtures involves many critical steps: consideration of chemical raw material purity as well as detailed impurity characterization; calculation of phase behavior for the calibration gas mixture; precise blending; and lastly, independent confirming analysis of the final calibration gas mixture.

Before starting, requested custom gas mixtures are first evaluated for potential phase problems using advanced computer modeling. Following this, the specialty gas mixture is precisely blended to exacting specifications on highly sensitive gravimetric scales. All calibration weights are traceable to the US-NIST (National Institute of Standards and Technology). Finally, the specialty gas mixture is analyzed using state-of-the-art analyzers to confirm that the blended and analyzed values agree with each other according to the stated product specifications.


Each manufacturing step we use as a calibration gas mixtures supplier must be constantly measured and validated. At MESA, every calibration gas mixture goes through at least seven defined stages during the manufacturing process. From raw material analysis through final mixture certification, results are measured, recorded, and then compared to strict quality control requirements based on each individual mixture. Several stages of the manufacturing process contain proprietary techniques perfected during our 30+ years' experience of specialty gas manufacturing.

What’s the difference between varying specialty gas manufacturers?

Many specialty gas manufacturers fail to monitor these steps closely enough to provide accurate results as calibration gas suppliers. Raw materials are accepted and adjusted according to the provider's specification sheet. This information is frequently misstated or inaccurate. Also, sub-par raw materials are often used in the manufacturing of specialty gases. This not only compromises the accuracy of the specialty gas but could impact critical components on your analyzer. MESA starts with high purity raw materials and carefully analyzes each pure gas for potential impurities. This ensures a quality calibration gas standard that is manufactured free of unwanted impurities.

Careful analysis of the calibration gas standard compared with multiple standards is a critical step in the specialty gas manufacturing process, and this is what makes us the premier calibration gas suppliers. Many companies may have few internal standards to inter-compare. Other companies may inter-compare with internal standards that fail to strictly optimize some of the critical phases mentioned above. 

The result can be an inaccurate standard confirmed by GC analysis. If both mixtures did not optimize the steps mentioned above, then the result is often confirmed, but an inaccurate calibration gas standard is produced. As a calibration gas mixtures supplier, we use both internal standards and reputable 3rd party manufacturers to inter-compare our products. This is an additional quality control step to ensure a reliable calibration gas standard has been manufactured.

Cylinder preparation is another critical step often overlooked. Cylinder preparation should be based on the individual calibration gas mixture. Many manufacturers take a single approach to cylinder preparation, often resulting in less than optimal conditions for the calibration gas standard. Over the years, MESA has developed several proprietary techniques for cylinder preparation, making sure that each cylinder has been prepared to optimize the performance of your custom gas mixture. 

Filling techniques vary greatly. A comprehensive commitment to quality is the principle that drives our work as a calibration gas mixtures supplier. MESA constantly evaluates new filling methods to determine which techniques produce the most accurate results. Our continuous evaluations of new techniques ensure that you will receive the most accurate calibration gas standards available in the market.

As a calibration gas supplier, our business is to market and provide quality specialty gases, equipment, and chemicals delivered directly to customers and/or through our worldwide distribution partners. It is our guiding principle that only the highest quality products will be offered to our clients. We emphasize that only excellent customer service will allow our profitable growth in this highly competitive industry.